Jakarta siap menyambut salah satu acara literasi terbesar tahun ini: Festival Puisi Esai Jakarta II. Acara yang akan berlangsung pada:
Hari/tanggal: Jumat & Sabtu, 13-14 Desember 2024
Waktu: 09.00 – 22.00 WIB
Tempat: PDS HB Jassin, Taman Ismail Marzuki, Jakarta
Dengan tema “Kesaksian Generasi Baru”, festival ini menjadi ajang berkumpulnya penulis, seniman, dan pecinta sastra untuk merayakan dan menggali makna dari puisi esai, sebuah bentuk karya sastra yang menggabungkan keindahan puisi dengan kekuatan esai.
Apa Itu Puisi Esai?
Puisi esai adalah genre sastra yang menggabungkan elemen puisi dan narasi berbasis fakta atau realita. Dalam puisi ini, penulis menyampaikan gagasan mendalam tentang isu sosial, budaya, atau kehidupan pribadi yang sering kali dilengkapi dengan catatan kaki sebagai referensi atau penjelasan. Bentuk ini tidak hanya indah secara bahasa, tetapi juga edukatif dan relevan dengan persoalan nyata yang dihadapi masyarakat.
Apa yang Akan Anda Temukan di Festival Ini?
Festival dua hari ini dirancang untuk semua kalangan, bahkan bagi mereka yang baru mengenal sastra. Berikut rangkaian kegiatan menarik yang bisa Anda nikmati:
- Peluncuran 37 Buku Puisi Esai
Penulis-penulis berbakat akan memperkenalkan karya terbaru mereka, memperkaya khasanah sastra Indonesia. - Penganugerahan “Ibukota Puisi Esai”
Kota yang berkontribusi besar terhadap perkembangan genre puisi esai akan mendapat penghargaan istimewa. - Puisi Esai Awards
Penghargaan bagi karya terbaik yang menginspirasi masyarakat dan membawa perubahan positif. - Penobatan Duta Puisi Esai
Tokoh sastra yang aktif mempromosikan puisi esai akan dinobatkan sebagai duta untuk menyebarkan semangat literasi ke seluruh negeri. - Diskusi Panel
Para penulis, akademisi, dan budayawan akan membahas bagaimana puisi esai menjadi cermin dan saksi dari generasi baru. - Penampilan Seni
Termasuk pembacaan puisi esai, pertunjukan musik, nyanyian puisi, pemutaran film, hingga penampilan teater. Semua ini dirancang untuk memberikan pengalaman seni yang menyentuh dan membangkitkan pemikiran.
Mengapa Harus Hadir?
Acara ini gratis dan terbuka untuk umum, jadi Anda tidak perlu menjadi pakar sastra untuk menikmatinya. Festival ini adalah ruang untuk belajar, menginspirasi, dan merayakan kreativitas. Tidak hanya itu, ini adalah kesempatan untuk bertemu dengan tokoh-tokoh sastra terkenal seperti Denny JA, Agus R. Sarjono, Okky Madasari, dan lainnya.
Untuk Anda yang Baru Terjun ke Dunia Sastra
Festival ini dirancang untuk menjangkau semua orang, termasuk mereka yang baru mengenal sastra. Acara seperti open mic puisi, pemutaran film, dan penampilan teater akan mempermudah Anda untuk memahami bagaimana sastra dapat menyentuh hati dan pikiran.
Jangan lewatkan kesempatan ini untuk menyelami dunia puisi esai dan mendapatkan inspirasi dari Kesaksian Generasi Baru. Ajak keluarga, teman, dan komunitas Anda!
Informasi lebih lanjut: Hubungi Amelia di 081286407824.
#FestivalPuisiEsaiJakarta #SastraUntukSemua #LiterasiIndonesia
At regular physiologic ranges of testosterone androgen receptors are saturated and the AASs results could
also be a consequence of different mechanisms somewhat than androgen receptors activation. High testosterone ranges might have an antagonist impact on glucocorticoid receptors, leading to
inhibition of glucose synthesis and protein catabolism.
Certainly, high dose AASs could displace glucocorticoids from
their receptors, lower proteins breakdown in muscular tissues, leading to a rise in muscle mass and muscle strength [18].
The appropriate dosage of testosterone can vary depending
on particular person components similar to age, physique composition, and goals.
For testosterone replacement remedy, doses typically vary from a hundred to 200 mg per
week. Nonetheless, bodybuilders typically use larger
doses, sometimes as a lot as 600 mg per week or more, to attain more vital muscle positive aspects and performance enhancements.
Testosterone, often thought-about the safest steroid choice for bodybuilding, serves
as the cornerstone of many steroid cycles. This hormone plays a vital
position in muscle growth, strength growth, and overall athletic performance.
Until natural testosterone ranges return to regular, users are advised to refrain from taking any other steroids and implement post-cycle therapy during this era.
This stack was believed to be one of the most distinguished
steroid cycles from the Golden Era, thought to have been utilized
by Arnold Schwarzenegger and other classic bodybuilders from the
Seventies. We have discovered this steroid cycle to be a more normal protocol
among intermediate steroid customers. Anadrol is an oral steroid, which makes it advantageous for people who wish
to circumvent injections. Anecdotally, we now have observed that first-time Anadrol cycles can add over 30
kilos to a user’s weight.
Nonetheless, research show that roughly 52% of
males report muscle loss when taking it (20).
Anavar has a significant influence on power, despite being a chopping steroid and
not inflicting dramatic weight acquire. If you are interested in purchasing oral steroids, it
may be very important speak to your physician about your wants and whether or not
this medication is right for you. Testosterone just isn’t suitable for girls to take due to its strong androgenic ranking.
We have additionally seen testosterone speed up male pattern baldness
in men, in addition to oily pores and skin and acne vulgaris.
Testosterone is an FDA-approved injectable anabolic steroid, typically prescribed in medicine for endogenous testosterone deficiency (5).
It’s important to talk with a well being care provider about the benefits versus the risks of those medicines.
These unwanted effects are most typical with oral corticosteroids and
may ease when you stop taking your medicines (under your doctor’s guidance).
However, prescription steroids should solely be used by the person a physician ordered them for.
Sharing your prescription or taking these medications prescribed to another person is
considered illegal.
To address this, testosterone undecanoate has recently
been formulated in a self-emulsifying drug delivery
system (SEDDS) to further improve lymphatic absorption and
scale back intra- and interindividual variation (10).
Nevertheless, it must be dosed twice daily to maintain physiological testosterone levels throughout the
day. An various technique centers round considerably retarding metabolism of the compound.
This structural modification significantly will increase oral
bioavailability, though it comes with hepatotoxicity (11).
Oral anabolic steroids like Winstrol (Stanozolol), Anavar (Oxandrolone), and Anadrol (Oxymetholone) belong
to a class of compounds generally identified as 17-alpha
alkylated (17-AA) steroids. These steroids are chemically modified to survive liver metabolism, allowing them to be taken orally—but with increased hepatotoxicity and strong HPTA suppression.
German scientists had beforehand observed Dianabol increasing muscular energy and energy, but at the value of excessive weight achieve.
Notice how the woman above didn’t truly lose any weight (+2 kg), yet she experienced dramatic fats loss.
We have seen ladies avoid virilization unwanted effects when taking Dianabol in low doses;
nevertheless, with trenbolone, masculinization is extra prone to happen. Trenbolone also has strong fat-burning
properties (39); thus, we have seen it successfully utilized in chopping cycles.
Generally, Dianabol isn’t beneficial for cutting, because the physique shall
be in a calorie deficit (catabolic).
The exploration of safer steroid options for bodybuilding sheds gentle on the advanced panorama of
efficiency enhancement. Whereas compounds like testosterone, Anavar, Primobolan, and HGH supply potential advantages, additionally
they include dangers that can’t be ignored.
The key takeaway is that even the most secure steroids should
be approached with caution, correct information, and ideally, medical supervision to minimize potential well being points.
While HGH is usually perceived as a safer alternative to anabolic steroids, it’s crucial to grasp that it nonetheless carries potential dangers and
side effects. However, unsupervised use or abuse can lead to severe well being
issues. This twin impact makes it particularly attractive for bodybuilders looking to obtain a extra outlined and sculpted physique.
References:
PedsElite
The HAARLEM research, nevertheless, discovered no interaction between blood stress and echocardiographic
parameters – in all probability as a result of the increase was mild
and of relatively short period (97). Future analysis is important to explore the efficacy of blood pressure-lowering treatment on this group of patients as no trial thus far has evaluated this.
When considering pharmacological therapy, angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) may
be preferrable over other blood pressure-lowering treatment as they do not affect exercise capability (98).
Additionally, they are not on the present record of prohibited substances and methods of the World Anti-Doping Association, which might – paradoxically
– be related for some AAS users. Alternatively, or additionally,
calcium channel blockers are a most well-liked choice
in athletes (98). The key question that continues to be to be answered is whether
or not excessive dosages of AAS further promote the event of male-pattern hair loss.
In the HAARLEM examine, self-reported alopecia increased
from 2% at baseline to 12% at the end of the cycle (39).
Identifying these components creates alternatives to construct rapport,
minimize harm, and finally progress to cessation. Many lesser-known,
steroid-producing plants are often marketed as T-boosters, similar to damiana
(Turnera diffusa; Passifloraceae) or Malaysian ginseng (Eurycoma
longifolia; Simaroubaceae). Damiana was reported to contain sitosterol 3-O-β-d-glucoside, whereas Malaysian ginseng has a lanostane by-product,
tirucallane (64 and 65, Figure 11). Again, there may be little or no proof that the compounds present
in extracts of those crops enhance endogenous T
ranges [106,107,108,109].
They may additionally be used off-label for stimulation of urge for food and to extend muscle mass in malignancy and purchased immunodeficiency syndrome (AIDS) (Ganesan et al.,
2023). The anabolic properties within anabolic
steroids are liable for muscle and tissue progress.
The androgenic side promotes masculinizing effects, similar to deepening of the voice and elevated body and facial hair.
Subsequently, a relatively low caloric food plan combined with weight and
cardio training mostly follows the bulking phase.
To prevent lack of muscle, the slicing section is accompanied
by a cutting cycle of anabolic steroids. Fat apposition, androgens within the
cutting cycle shouldn’t be susceptible to aromatization.
Due To This Fact, trenbolone, stanozolole and drostanolone are usually thought to be cutting agents.
Clark and Henderson (2003) have summarized the literature with respect to the consequences of anabolic steroids on the neural circuits that
underlie behavioural effects; their evaluation focusing on animal
fashions and steroid publicity that mimic human abuse
regimes. Androgen receptors mediate the effects of
anabolic steroids within the mammalian mind; the expression of progestogen and oestrogen receptors may also be affected.
Our editors will evaluation what you’ve submitted and determine
whether or not to revise the article. All kinds of research designs have been considered
due to the anticipated lack of high-quality managed
trials. The evaluate was undertaken following Arksey
and O’Malley’s guidance for scoping evaluations,
which knowledgeable the event of evaluation methods and
write-up of strategies and findings [86]. This is an open entry article distributed
beneath the phrases of the Creative Commons Attribution License, which allows
unrestricted use, distribution, and reproduction in any medium, offered the original creator and supply are credited.
In the early years of anabolic steroid development, there wasn’t
a normal methodology to how totally different steroids had been tested or how they have been measured for energy.
After administration of the steroid being tested, varied physique
elements and muscles of a rat could be analyzed.
Since testosterone was thought-about the standard for testing,
the tissues could be compared to tissues that have been exposed to testosterone.
The increase in muscle size and weight of the levator ani
would give an accurate indication of the steroid’s anabolic capabilities.
Over the years, it has turn into apparent that the endocrinology of
skeletal muscle is very advanced, and there is a delicate steadiness between synthesis and
breakdown during growth, health, disease and ageing, as thought-about by Sheffield-Moore
and City (2004). Eisenberg and Gordan (1950) proposed the usage of the rat levator ani muscle as a bioassay
of protein anabolic activity; the anatomical drawings from the dissection of the male rat, displaying the location of this muscle, the prostate and seminal
vesicles are displayed in this paper.
The anabolic effects of AAS are mediated largely in part by altered regulation of the transcription of target genes responsible for the binding of DNA required to
stimulate MPS activation by SM ARs, a lot in the identical method as endogenous androgens (20, 29).
Additional, AAS administration has been observed to have a dose-dependent effect, with larger doses leading to
higher anabolic results (16). Probably the best check for establishing a
causal position of AAS is thru placebo-controlled
trials. In the early Nineteen Nineties, a few such trials assessed psychological
measures in volunteers receiving doses of testosterone
up to 300 milligrams per week underneath blinded circumstances.
Such a history is definitely missed when evaluating males who are older and
not visibly athletic. In one recent research of 223 men admitted to a basic
substance abuse treatment unit (Kanayama et al.,
2003a), 29 (13%) reported a historical past of AAS use on a research
screening interview, however in only four of these
instances was this historical past famous within the physician’s admission evaluation. As the first giant wave of former AAS customers now moves into middle age, it is going to be necessary to obtain more systematic knowledge on the long-term psychiatric and medical penalties of
this form of substance abuse.
Accumulating proof means that long-term use of supraphysiologic doses of
AAS may have antagonistic results on a quantity of organ methods, resulting in each medical
and psychiatric pathology. Importantly, accumulating proof suggests that some
of these effects could persist lengthy after last AAS exposure.
However, the frequency and severity of AAS-induced morbidity and mortality is still poorly understood,
largely as a end result of these effects may not declare
themselves till customers enter center or old age – and investigators have examined at most small samples of growing older
AAS users. But this example is poised to vary, as hundreds of
1000’s of former (and typically nonetheless current) illicit AAS users begin to move the age
of 45. As this wave of aging users approaches, it is crucial to provoke bigger
and more systematic research of the long-term effects
of AAS, in order that we will higher inform both the current and future generations.
In other words, the hypothalamus works exhausting to keep T levels inside a
‘physiological regular limit’. Once the pituitary gland receives this message it takes a run up and propels its personal hormone into the bloodstream
like a slingshot. If your T levels are getting low,
your hypothalamus sends a message to your pituitary gland (situated
beneath the hypothalamus in your brain) utilizing a hormone known as GnRH.
References:
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