SIARAN PERS
Kamis, 22 Agustus 2024
JAKARTA – Perkumpulan Penulis Indonesia SATUPENA telah menerbitkan buku “PILPRES 2024: Kesaksian Para Penulis,” yang merupakan kumpulan karya 76 penulis tentang Pemilihan Presiden 2024.
Hal itu dinyatakan Sekjen SATUPENA Satrio Arismunandar, yang juga menjadi editor buku tersebut, di Jakarta, Kamis, 22 Agustus 2024.
Menurut Satrio, Pemilu dan Pilpres 2024 adalah peristiwa besar. Dengan segala dinamikanya, hasil Pemilu dan Pilpres 2024 akan mewarnai, bahkan menentukan masa depan Indonesia, sebagai negara demokrasi nomor tiga terbesar di dunia setelah India dan Amerika Serikat.
Menyadari arti penting Pilpres 2024 dalam sejarah bangsa, ungkap Satrio, pada Februari 2024, Ketua Umum SATUPENA Denny JA telah menggagas penerbitan buku “PILPRES 2024: Kesaksian Para Penulis,” yang berisi kumpulan artikel dari para penulis.
“Awalnya, cuma ditarget buku berisi kumpulan 25 tulisan. Tetapi dalam prosesnya, ternyata
minat para penulis untuk terlibat dalam penulisan buku ini membludak,” ujar Satrio.
Sebanyak 133 penulis, yang bukan cuma anggota SATUPENA, menyatakan minatnya untuk berkontribusi.
Sampai batas waktu 12 Maret 2024, dari 133 penulis yang menyatakan minatnya itu tidak semua bisa mengirim tulisan. “Jumlah naskah yang akhirnya betul-betul sampai di tangan penyunting ada 77 tulisan,” lanjut Satrio.
Satrio menjelaskan, dari 77 tulisan yang mereka kirim, yang dianggap layak untuk dimasukkan ke buku ini ada 74 tulisan. Kebetulan ada satu tulisan yang ditulis oleh 3 orang, sehingga total ada 76 penulis yang berkontribusi lewat 74 tulisan pada buku ini.
Buku setebal 410 halaman ini hanya dibuat dalam format PDF, tidak dicetak. “Bagi penulis atau pembaca yang membutuhkan buku versi cetak, dipersilakan untuk mengeprint sendiri,” ucap Satrio.
Satrio berharap, semua tulisan di buku ini –dengan segala kelebihan dan kekurangannya—benar-benar bisa menjadi bukti kesaksian para penulis Indonesia tentang peristiwa bersejarah Pilpres 2024.
Mengutip sastrawan Pramoedya Ananta Toer, Satrio menyatakan, “Orang boleh pandai setinggi langit, tapi selama ia tidak menulis, ia akan hilang di dalam masyarakat dan dari sejarah. Menulis adalah bekerja untuk keabadian.”
“Begitu pentingnya meninggalkan jejak tertulis dalam sejarah. Apalagi kesaksian tertulis terhadap sebuah peristiwa besar seperti Pilpres 2024, yang punya arti signifikan bagi 279,5 juta rakyat Indonesia,” ujar Satrio.
Ditambahkan Satrio, proses Pemilu dan Pilpres 2024 di Indonesia diamati secara serius oleh dunia internasional karena posisi Indonesia dianggap penting.
“Mungkin kita di dalam negeri tidak begitu menyadari, tetapi faktanya posisi Indonesia kini sudah semakin dipandang dalam hubungan internasional. Peningkatan status Indonesia ini sejalan dengan makin besarnya kekuatan ekonomi negeri ini,” lanjut Satrio.
Menurut proyeksi Standard Chartered, PDB Indonesia pada 2030 diprediksi mencapai $10,1 triliun atau naik hampir 3 kali lipat dari tahun 2017 ($3,2 triliun) dan akan berada di peringkat ke-4 negara dengan perekonomian terbesar dunia. Peringkat tersebut dihitung menurut nominal produk domestik bruto (PDB) atas dasar purchasing power parity. ***
This peptide functions by participating with
quite a few molecular pathways, including the
modulation of gene expression, mitigation of inflammation, and modulation of development factors essential for tissue restoration. In the evolving
panorama of regenerative supplements, Dr. Seeds BPC-157 has established itself as a noteworthy contender.
This peptide supplement has garnered attention for its potential therapeutic properties and comprehensive approach
to tissue restoration. With the recent merger between Dr.
Seeds and Infiniwell, customers are interested by what this implies for
product high quality, availability, and efficacy. Me, Joe
Schmoe, was skeptical at first once I heard about Pure Therapro Rx Acute Harm.
I injured my tendon whereas enjoying basketball and was
afraid I wouldn’t have the power to get again within the sport for weeks.
Nevertheless, more studies are needed to totally perceive
its effectiveness in treating nerve accidents. As always,
it’s essential to seek the guidance of with a healthcare professional before utilizing any complement for specific medical conditions.
Not Like many peptides that get damaged down in the
digestive tract, BPC-157 is not destroyed by abdomen acid.
In reality, it’s stable in human gastric juice for over 24 hours.four This means it could probably be
efficient taken orally (as a pill) in addition to
being utilized by injection. BPC-157 has no sequence overlap with other gut
peptides and works in extremely tiny doses (micrograms to nanograms
in animal studies).5 These uncommon properties
make it an intriguing candidate as a therapeutic agent.
BPC‑157 is an artificial peptide consisting of 15 amino acids, initially isolated from a segment of
physique safety compound present in gastric juice.
As a particular notation, BPC 157 had no effect on regular blood strain [61,62].
Thus, the effect on blood strain of BPC 157 remedy may be effectively associated to the resolution of particular sick situations, probably depending on the normalization of the guts function,
as cytoprotection application is in a position to
normalize either disturbed blood stress or hypotension. BPC 157
attenuated the bleeding prolongation induced by
anti-coagulants, anti-thrombotic agents, and
NOS-substrate L-arginine, alone or with amputation (tail, leg), without affecting coagulation pathways [58,fifty nine,60].
Likewise, BPC 157 attenuated the bleeding from the leg or tail amputation [58,59,60], organ perforation or hemorrhagic mucosal lesions (cecum,
stomach) [32,33], spinal twine compression [35,36],
and intracerebral or intraventricular bleeding [19,24,27,29,31,37,38,39,40].
Moreover, BPC 157 might particularly keep the perform of thrombocytes (as
noted in aggregometry and thromboelastometry studies) [60].
Given with aspirin, clopidogrel, or cilostazol in rats, BPC 157 counteracted their inhibitory results on aggregation activated by arachidonic acid, ADP, collagen, and arachidonic acid/PGE1 [60].
Thus, given the preliminary infarct induction and re-infarction (the myocardial lesions after two isoprenaline applications)
and that BPC 157 markedly counteracts myocardial
isoprenaline lesions, the findings provide multidirectional
evidence [38].
Nonetheless, in revealed analysis so far, BPC-157 administration has
produced minimal unwanted effects in both nonhumans and humans.
Particularly, a evaluation of clinical trials on the usage of
BPC-157 has characterised it as safe both in treating inflammatory bowel illness and wound therapeutic, noting that no occasions of toxicity had been reported all through those trials [12].
Because of those properties, isolated BPC-157 is of nice
curiosity to researchers. The peptide reveals potential in numerous
applications outdoors of the GI tract, including in its promotion of
therapeutic, muscle progress and restore, and damage recovery.
Therefore, using BPC 157 will not be the best selection, especially in conditions the
place we are not conscious of the presence of cancer
cells in our physique.
Providing sturdy interrelations between the arrhythmias, coronary heart failure,
and thrombosis [164], assuming the venous and arterial thrombosis as
two elements of the identical illness [165,166], the BPC 157 counteracting effect may be reciprocally associated.
Thus, in coronary heart failure therapy, the therapeutic impact of BPC 157 administration might counteract
the escalating thrombosis as a shared common point [19,24,27,29,31,37,38,39,40].
This may be the consequent reversal of the overall stasis
(i.e., in any other case giant volumes trapped within the damaged abdomen, CNS,
and portal and caval vein tributaries, which can additionally perpetuate the mind and coronary heart ischemia).
Along with this, it could be the reversal of the failed activation of the collateral bypassing pathways.
In coronary heart disturbances, steady gastric pentadecapeptide BPC 157 especial therapy effects combine the remedy
of myocardial infarction, coronary heart failure, pulmonary hypertension arrhythmias, and
thrombosis prevention and reversal. As a vital novelty noted within the vascular studies, there was the activation of the collateral pathways.
As a half of the counteraction of the extreme vessel and multiorgan failure syndrome, counteracted had been the mind, lung, liver, kidney,
gastrointestinal lesions, and specifically, the counteraction of the
guts arrhythmias and infarction. BPC 157, generally recognized as the “Body Protection Compound”, is
a pentadecapeptide isolated from human gastric juice that
demonstrated its pleiotropic helpful results in various preclinical fashions mimicking medical situations, corresponding to tissue injury, inflammatory bowel disease,
or even CNS disorders. Unlike many other medicine, BPC 157 has a desirable security profile, since only a few unwanted effects have been reported following its administration.
In contrast to PDGF-BB, in diabetic wounds, induced by alloxan software, BPC 157 largely promoted mature collagen in granulation tissue (Seveljevic-Jaran et
al., 2006) (note, previously, BPC 157 healed alloxan-induced gastric
lesions in rats (Petek et al., 1999)). In addition, BPC 157 has a particular useful impact when confronted with
the major vessel occlusion (Duzel et al., 2017;
Amic et al., 2018; Drmic et al., 2018; Vukojevic et al., 2018;
Sever et al., 2019; Berkopic Cesar et al., 2020; Gojkovic et al.,
2020; Kolovrat et al., 2020; Vukojevic et al., 2020).
Likewise, reestablished blood move may actually contribute to the rapid recovery effect noted.
These results can help maintain coaching consistency and scale back time lost to overuse accidents or soft tissue pressure.
Growth Hormone Interaction BPC-157 does not immediately increase development hormone
secretion. Nonetheless, by enhancing restoration, decreasing inflammation, and accelerating tissue restore, it might not directly help training capability
and long-term efficiency by helping athletes keep energetic and recuperate extra efficiently.
In more critical cases—such as persistent accidents, post-surgical restoration, or nerve-related issues—higher doses up to 1,000
micrograms per day may be really helpful. For these eventualities, many customers benefit from splitting the whole dose into two
or extra administrations all through the day to keep up steady blood levels and maximize effect.
For mild to average considerations, similar to general irritation, wellness
support, or light damage recovery, a common beginning dose ranges from 250 to 500 micrograms per day.
Like many research peptides, injection of BPC-157 has traditionally been the favored route of administration as
a outcome of compound’s instability and consequent low oral bioavailability.
Nonetheless, a extremely secure type of BPC-157 called BPC-157 arginate has recently been developed, exhibiting oral bioavailability of
over 90%. Given the peptide’s notable gastroprotective results,
it could be well suited to this novel capsular form [8, 9, 10].
Now, let’s study in larger detail what it does to your body and how it impacts
you generally. Originally, BPC 157 originates from the body’s gastric juices,
and we all know that this can be a very acidic substance that may even digest steel.
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